Esprit or L'Esprit may refer to:

• the French for Spirit; as a loanword:
  • Enthusiasm, intense interest or motivation
  • Morale, motivation and readiness
  • Geist "mind/spirit; intellect"
• Esprit (name), a given name and surname
• Esprit (magazine), a periodical

• L'esprit (In the Nursery album)

• Lotus Esprit, a car
• Esprit Holdings, a clothing manufacturer
• Esprit D'Air, a Japanese metal band
• European Strategic Program on Research in Information Technology, a cooperative government program
• Estimation of signal parameters via rotational invariance techniques, a signal processing method
• European System Providing Refueling, Infrastructure and Telecommunications, a planned module of the Lunar Gateway